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  • Shouyan WANG
  • Research Direction:Neural engineering, Digital health
  • Email:shouyan@fudan.edu.cn
  • Website:
  • Brief Introduction:Professor Shouyan Wang received the BSc degree in Biomedical Engineering in 1994, and the Msc and PHD degree in Physiology from the Fourth Military Medical University, Xi’an, China, in 1997 and 2000, respectively. He was a Postdoctoral Research Fellow in the Neurosurgery Department of JR Hospital and Department of Physiology, Anatomy and Genetics at University of Oxford from 2002 to 2007. He worked as a Lecturer in the institute of Sound and Vibration Research at University of Southampton from 2007 to 2012. He became a Professor at Suzhou Institute of Biomedical Engineering and Technology of Chinese Academy of Sciences, and the Directors of the Biomedical Electronics Department, Key Lab of Neural Engineering and Technology at Suzhou from 2012 to 2017. He joined Fudan University in 2017 and has been the Director of Neural and Intelligent Engineering Centre at ISTBI. His research focuses on the intelligent neuromodulation of deep brain stimulation for neurological diseases, including identification of biomarkers from human deep brain local field potentials, technology development of miniaturized adaptive electrical or optical stimulator, and monitoring of motor or sensory behaviors with wearables devices. Professor Shouyan Wang works toward integrating engineering, neuroscience, neurology and neurosurgery to advance the translational research from deep brain stimulation technology to neurological disease treatment.
  • Achievement:

    Papers Published in the Past 5 Years

    1.Yingnan Nie, Huichun Luo, Xiao Li, Xinyi Geng, Alexander L. Green, Tipu Z. Aziz, Shouyan Wang*. Subthalamic dynamic neural states correlate with motor symptoms in Parkinson’s Disease,Clinical Neurophysiology, 2021, 132 (11), 2789-2797.

    2.Yingnan Nie, Xuanjun Guo, Xiao Lie, Xinyi Geng, Yan Li, Zhaoyu Quane, Guanyu Zhu, Zixiao Yin, Jianguo Zhang, Shouyan Wang*. Real-time removal of stimulation artifacts in closed-loop deep brain stimulation,Journal of Neural Engineering,2021, 18(6), 066031.DOI10.1088/1741-2552/ac3cc5.

    3.Zhang H, Wang J, Geng X, Li C and Wang S (2021). Objective Assessments of Mental Fatigue During a Continuous Long-Term Stress Condition.Frontiers in Human Neuroscience. 15:733426. doi: 10.3389/fnhum.2021.733426

    4.Jingying Wang, Huichun Luo, Rasmus Schülke, Xinyi Geng, Barbara J Sahakian, Shouyan Wang*. Is Transcranial Direct Current Stimulation, Alone or in Combination with Antidepressant Medications or Psychotherapies, Effective in Treating Major Depressive Disorder? — A systematic review and meta-analysis,BMC MEDICINE, 2021, 19(1),319.DOI10.1186/s12916-021-02181-4

    5.Huichun Luo, Yongzhi Huang, Alexander L. Green, Tipu Z. Aziz, Xiao Xiao, Shouyan Wang*. Neurophysiological characteristics in the periventricular/periaqueductal gray correlate with pain perception, sensation, and affect in neuropathic pain patients,NeuroImage Clinical, 2021, 32:102876.DOI10.1016/j.nicl.2021.102876

    6.Deniz Vatansever, Shouyan Wang, Barbara J Sahakian. Covid-19 and promising solutions to combat symptoms of stress, anxiety and depression, NEUROPSYCHOPHARMACOLOGY(综述)

    7.Zhu, JLL,Schulke, R ,Vatansever, D ,Xi, DY ,Yan, JJ , Zhao, HQ, Xie, XH , Feng, JF , Chen, MY ,Sahakian, BJ *, Wang, SY *. Mindfulness practice for protecting mental health during the COVID-19 pandemic,TRANSLATIONAL PSYCHIATRY, 2021, 11(1): 329. DOI:10.1038/s41398-021-01459-8.

    8.Yanan Sui, Ye Tian, Wai Kin Daniel Ko, Sheyann Wang, Fumin Jia, Andreas Horn, Dirk De Ridder, Ki Sueng Cho, Ausaf A. Bari, Shouyan Wang, Clement Hamani, Kenneth B. Baker Andre G. Machado, Tipu Z. Aziz, Erich Talamoni Fonoff, Andrea A. Kühn, Hagai Bergman, Terence Sanger, Hesheng Liu*, Suzanne N. Haber* and Luming Li *. Deep Brain Stimulation Initiative: Toward Innovative Technology, New Disease Indications, and Approaches to Current and Future Clinical Challenges in Neuromodulation Therapy,Frontiers in Neurology,2021,11,597451.DOI10.3389/fneur.2020.597451

    9.Linbo Wang, PhD#, Wei Cheng, PhD#*, Edmund Rolls, DPhil, DSc, Fuli Dai, MSc, Weikang Gong, PhD, Jingnan Du, MSc, Wei Zhang, BSc, Shouyan Wang, PhD, Fengtao Liu, MD, Jian Wang, MD, Peter Brown*, MD and Jianfeng Feng*, PhD.Association of specific biotypes in patients with Parkinson disease and disease progression,Neurology, 2020, 95(11), E1445-E1460.

    10.Poon, Chi Him; Tan, Shawn Zheng Kai; (...); Lim, Lee Wei. A Brief Comparative Look at Experimental Memory Editing Techniques for Cognitive Dysfunction, 2021, Current Alzheimer research

    11.Z Xiao,Y Liu,C Li,L Zhang,S Wang*,X Xiao*.A Two-Stream Action Recognition Network Based on Temporal Shift and Split Attention.Computer Systems&Applications,2021.(IF: 0.506)

    12.Z Zhao,J Wang,X Geng,T Zhu,S Wang*.Depression Recognition Method Based on Acoustic Signal Analysis Integrating Attention Mechanism and Bi-LSTM.Journal of Fudan University(Natural Science),2021(已录用).

    13.H Luo, Y Huang, X Xiao, W Dai, Y Nie, X Geng, A Green, T Aziz, S Wang*. Functional dynamics of thalamic local field potentials correlate with modulation of neuropathic pain,European Journal of Neuroscience, 2020, 51(2) :624-628.

    14.L Shen,X Geng,S Wang *.Epileptic States Recognition using Transfer Learning and Dilated CNN.Chinese Journal of Biomedical Engineering,2020,39(06):700-710. (IF: 0.89).

    15.J Wang,D Gong,H Luo,W Zhang,S Wang*. Measurement of step angle for quantifying the gait impairment of Parkinson's disease by wearable sensors: Controlled study,JMIR mHealth and uHealth, 2020, 8(3): e16650.

    16.Han Zhang, Chuantao Li, Wei Liu, Jingying Wang, Junhong Zhou and Shouyan Wang*, A Multi-Sensor Wearable System for the Quantitative Assessment of Parkinson’s Disease,Sensors.2020,20(21), DOI:10.3390/s20216146.

    17.Deniz Vatansever, Shouyan Wang and Barbara J. Sahakian. Covid-19 and promising solutions to combat symptoms of stress, anxiety and depression,Neuropsychopharmacology, 2020:1-2.

    18.Shen L, Geng X, Luo H,J Wang,S Wang*. Epileptic States Recognition Using Transfer Learning,2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2019,2539-2542.

    19.Jingying,Wang,Dawei,Gong,Wenbin,Zhang,Han,Shouyan*. Quantifying the influence of DBS surgery in patients with Parkinson's disease during perioperative period by wearable sensors.Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2019,0:3311-3314.

    20.GuanYu Zhu,XinYi Geng,RuiLi Zhang,YingChuan Chen,YuYe Liu,ShouYan Wang*,JianGuo Zhang*. Deep brain stimulation modulates pallidal and subthalamic neural oscillations in Tourette's syndrome.Brain and Behavior, 2019, 9(12): e01450.

    21.Huiling Tan*, Jean Debarros, Shenghong He, Alek Pogpsyan, Tipu Z.Aziz, Yongzhi Huang, Shouyan Wang, Lars Timmermann, Veerle Visser-Vandewalle, David J.Pedrosa, Alexander L.Green, Peter Brown**. Decoding voluntary movements and postural tremor based on thalamic LFPs as a basis for closed-loop stimulation for essential tremor.Brain Stimulation, 2019,12(4):858-867.

    22.R Zhang,J Zhang*,S Wang*.Deep Brain Stimulation in the Treatment of Dystonia in Children:Current Status and Prospects.Chinese Journal of Neurosurgery|Chin J Neurosurg,2019(01):103-106.

    23.X Geng, X Xu, Z Ling*, A Horn, N Li, P Brown, S Wang*. Intra-operative characterisation of subthalamic oscillations in Parkinson's disease.Clinical Neurophysiology Official Journal of the International Federation of Clinical Neurophysiology, 2018, 129(5):1001. (封面文章)

    24.G Zhu,X Geng,T Zheng,Y Chen,S Wang*,J Zhang*. Characteristics of Globus Pallidus Internus Local Field Potentials in Hyperkinetic Disease.Frontiers in Neurology, 2018, 9:934.

    25.Q Deng,Y Yu,L Li,X Zhao,Y Liu,Q Jiang,S Wang*.Wireless Motion Sensor Node Based on CC3200 and Optimization of Power Consumption.Industrial Control Computer,2018,31(03):116-118.

    26.S Ge, X Geng, X Wang, N Li, L Chen, X Zhang, Y Huang, Y Li, S Wang*, G Gao*.Oscillatory local field potentials of the nucleus accumbens and the anterior limb of the internal capsule in heroin addicts. Clinical Neurophysiology, 2018,129(6):1242-1253.

    27.K Zhang,B Feng,YP Zhang,YZ Huang,SY Wang*,L Long,Y Li,X Li,Y Dai,H Yang. Pattern Identification of Subthalamic Local Field Potentials in Parkinson's Disease.Itm Web of Conferences, 2017, 12:02004.

    28.Li L, Liang L,SYWang*. Multi-sensor wearable devices for movement monitoring in Parkinson's disease.International IEEE/EMBS Conference on Neural Engineering. IEEE, 2017,70-73.

    29.H Luo,X Du,Y Huang,A Green,S Wang*. Dynamic synchronization state identification.2017 8th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2017,525-528.

    30.Huichun Luo,Xueying Du,Yongzhi Huang,Shouyan Wang*. Dynamic synchronization state discrimination in local field potentials of neuropathic pain.2nd IET International Conference on Biomedical Image and Signal Processing(ICBISP 2017). 2017,12:237.

    31.X Tang,Y Zhang,L Li,L Qian,S Wang*.Rapid development of neural informationreal-time processing platform.Transducer and Microsystem Technologies,2017,36(11):1-5.

    32.Luo, H.,Du, X.,Huang, Y.,Green, A.,Aziz, A.,Wang S*.Dynamic neural state identification in deep brain local fields potentials by wavelet packet transform,Brain Stimulation, 2017, 10(2):438-439.

    33.Huang YZ,Green AL, Hyam J, Fitzgerald J,Aziz TZ , WangSY*. Oscillatory neural representations in the sensory thalamus predict neuropathic pain relief by deep brain stimulation.Neurobiology of Disease, 2017, 109: 117-126.

    34.X Geng, J Zhang, Y Jiang, K Ashkan, T Foltynie, P Limousin, L Zrinzo, A Green, T Aziz, P Brown, S Wang*. Comparison of oscillatory activity in subthalamic nucleus in Parkinson’s disease and dystonia.Neurobiology of Disease, 2017, 98: 100-107.

    35.K Zhang,X Du,Y Huang,H Luo,S Wang*.Feature Detection of Subthalamic Local Field Potentials in Parkinson's Disease.Space Medicine & Medical Engineering,2017,30(03):208-213.

    36.Qifan Bai, Huijun Zhang, Chengjie Mao, Liang Li, Qian Yu, Baoteng Xu, Tianyu Shen, Chunfeng Liu, Shouyan Wang*. Quantitative assessment of Parkinson's disease with multiple wearable devices.IEEE International Conference on Signal Processing, 2017, 1848-1851.


    Intellectual Property

    Software Copyright

    1.王守岩、聂英男,智能脑深部电刺激平台软件,2018SR79449。(已授权)



    Patent for Invention

    1.王守岩、罗回春、黄永志、聂英男,一种基于脑部电信号构建疼痛状态预测模型的方法,201811066031.1。(已授权)

    2.王守岩、刘伟、张晗,具有智能自适应功能的便携式闭环脑深部刺激器系统,201810994051.9。(已授权)

    3.王守岩,沈雷,一种神经生理信号的生成和识别方法,201910044069.7。(已授权)

    4.王守岩、聂英男、罗回春,一种非侵入式闭环经颅电刺激装置,201810910152.3。

    5.王守岩、张晗、刘伟,一种多功能耳迷走神经刺激仪,201810911083.8。

    6.王守岩、沈雷,一种基于迁移学习和空洞卷积的癫痫状态识别方法,201910043745.9。

    7.王守岩、聂英男,一种基于多目视觉定位的增强现实交互系统,201911391144.3。

    8.王守岩、宋元明,便携式经颅音乐振动刺激发生设备,202010700306.3。

    9.王守岩、张晗,一种智能康复训练指导系统,202011170893.6。

    10.王守岩、李岩,一种听视觉协同的人形机器人头部定向方法,202010993992.8。

    11.沈雷、王守岩,一种基于迁移Softmax回归的癫痫状态识别方法,2021108509912。

    12.沈雷、王守岩,一种基于目标相似度分布调整的癫痫状态识别方法,202111104344.3。

    13.刘伟、王守岩、权昭宇,一种闭环深部脑刺激伪迹抑制系统及方法,202111074246.X。

    14.权昭宇、王守岩、刘伟,一种自适应闭环深部脑刺激方法、装置及电子设备,202111101877.6。

    15.郭轩君、聂英男、李霄、王守岩,一种神经信号实时去除刺激伪迹的方法、装置及介质,202111030359.X。

    16.徐君宙、王守岩、牛琦玉,脑刺激响应模型构建方法、响应方法、装置及电子设备,202111101876.1。

    17.李岩、聂英男、刘伟、王守岩,一种基于稳态视觉诱发电位的沟通系统,202110825498.5。

    18.张睿俐、耿馨佚王守岩,基于肌电信号反馈的智能定量给药电针注射设备,202110884904.5。

    19.赵张、汪静莹、王守岩、刘伟,一种基于Attention与Bi-LSTM的语音抑郁状态识别方法,202110855540.8。

    20.刘伟、王守岩、张晗,一种基于多信号的闭环深部脑刺激系统,202111030360.2。

    21.刘伟、王守岩、李岩,基于多信号的闭环深部脑刺激方法、装置、系统及设备,202111030407.5。

    22.张晗、王守岩、刘伟,婴儿状态监护及自动报警系统,202111050122.8。

    23.赵张、王守岩、汪静莹、刘伟,基于特征选择与迁移学习的语音抑郁状态识别方法,202110801507.7。

    24.牛琦玉、王守岩、徐君宙,一种动物坐骨神经结扎装置,202110863886.2。

    25.赵张、王守岩、刘伟,一种基于多模态融合的抑郁状态识别方法,202111174280.4。



    Utility Model Patent

    1.刘伟、王守岩、聂英男,一种闭环深部脑刺激伪迹抑制电路,202122220752.7。

    2.张晗、王守岩、刘伟,婴儿状态监护及自动报警系统,202122163166.3。