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人员

  • 李霄
  • 研究方向:神经疾病的调控与干预
  • 电子邮箱:lixiao.se@163.com
  • 个人网站:
  • 简要介绍:2011年至2018年于中国科学院神经科学研究所担任助理研究员,主要研究方向为孤独症谱系障碍动物模型的建立以及疾病机制的探索。2018年至2022年于复旦大学就读博士研究生,毕业后在校从事博士后工作,在此期间的主要研究方向为建立孤独症相关的神经电生理活动特征,通过神经电刺激干预改善孤独症的疾病表型及探索相关的神经机制。目前已以第一作者或共同第一作者在Nature、Science Bulletin,Neuroscience Bulletin等期刊上发表论文7篇,以共同作者在Science Advances,ACS Applied Materials & Interfaces等期刊上发表多篇论文。
  • 代表成果:

    [1]Xiao Li, Yingnan Nie, Qiyu Niu, Xuanjun Guo, Zilong Qiu*, Shouyan Wang*. Abnormal

    Prefrontal Neural Oscillations are Associated with Social Deficits in MECP2 Duplication Syndrome,Neuroscience Bulletin, 2022, 38(12): 1598-1602.

    [2]Xiao Li; Yingnan Nie; Zilong Qiu; Shouyan Wang*; Human MECP2 transgenic rats show

    increased anxiety, severe social deficits, and abnormal prefrontal neural oscillation stability,

    Biochemical and Biophysical Research Communications, 2023, 648: 28-35.

    [3] Shihao Wu#,Xiao Li#, Dongdong Qin, Linheng Zhang, Tianlin Cheng, Zhifang Chen, Binbin Nie, Xiaofeng Ren, Jing Wu, Wenchao Wang, Yingzhou Hu, Yilin Gu, Longbao Lv, Yong Yin*, Xintian Hu*, Zilong Qiu*. Induction of core symptoms of autism spectrum disorder by in vivo CRISPR/Cas9-based gene editing in the brain of adolescent rhesus monkeys.Science Bulletin, 2021, 16.

    [4] Hao Li#, Shihao Wu#, Xia Ma#,Xiao Li#, Tianlin Cheng, Zhifang Chen, Jing Wu, Longbao Lv, Ling Li, Liqi Xu, Wenchao Wang, Yingzhou Hu, Haisong Jiang, Yong Yin*, Zilong Qiu*, Xintian Hu*. Co-editing PINK1 and DJ-1 Genes Via Adeno-Associated Virus-Delivered CRISPR/Cas9 System in Adult Monkey Brain Elicits Classical Parkinsonian Phenotype.Neuroscience Bulletin, 2021, 37(9): 1271-88.

    [5] Zhen Liu#,Xiao Li#, Juntao Zhang, Yijun Cai, Tianlin Cheng, Cheng Cheng, Yan Wang, Chenchen Zhang, Yanhong Nie, Zhifang Chen, Wenjie Bian, Ling Zhang, Jianqiu Xiao ,Bin Lu, Yuefang Zhang, Xiaodi Zhang, Xiao Sang, Jiajia Wu, Xiu Xu, Zhiqi Xiong, Feng Zhang, Xiang Yu, Neng Gong, Wenhao Zhou, Qiang Sun* & Zilong Qiu*, Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2.Nature, 2016, doi:10.1038.