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Hesheng Liu: 个体脑功能网络与个性化医学

报告人: Hesheng Liu
讲者简介: Hesheng Liu is an Associate Professor at Harvard Medical School and Director of the Laboratory For the Study of the Brain Basis of Individual Differences at Massachusetts General Hospital. He received his B.S., M.S., and Ph.D degrees from Tsinghua University, China. His research focuses on developing novel neuroimaging and computational tools to reveal brain functional architecture in individual subjects. A major goal of his work is to localize functional networks in individual subjects to guide surgical intervention. Another theme in his lab is to identify personalized neuromodulation targets for brain disorders and study functional changes in individual patients after neuromodulation treatments. Dr. Liu
报告地点: Room 2201,East Main Building of Guang-Hua Tower
报告时间: 2018.8.17, 14:30
报告摘要: A major obstacle for exploring subtle aspects of network organization and translating insights into clinical applications is the lack of tools for mapping networks in individual subjects. We evaluated inter-individual variability in brain functional organization and developed a novel brain parcellation approach to accurately map functional regions at the individual level using resting-state fMRI. Based on the subject-specific functional regions, we were able to identify connectivity markers for cognitive ability in healthy subjects and clinical symptoms in various psychiatric disorders. These individually-identified functional circuits may lead to novel, personalized targets for neuromodulation treatments. Finally, I will briefly discuss our data on evaluating the effect of deep brain stimulation (DBS) on individual patients’ functional networks.