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  • 简要介绍:David Waxman carries out research work in quantitative biology using mathematical and computational methods. Since July 2011 he has been working full time in Fudan University, Shanghai, initially under the Chinese Government Foreign Expert (Qianren) Program. He has published research papers in well-known journals including Nature, Science, PNAS, Genetics and Evolution. He has served on the Editorial Board of journals such as Science, American Naturalist, Journal of Theoretical Biology and Theoretical Population Biology.
  • 代表成果:

    Selected Publications

    For a complete list, including downloadable versions (in PDF), clickhere

    Evolutionary Control:

    Targeted Change of Allele Frequencies in Natural Populations Using Externally Directed Evolution

    Journal of Theoretical Biology 419: 362-374 (2017) with Hassan Shafiey and Toni Gossmann.

    A Modified Wright-Fisher Model that Incorporates Ne:

    A Variant of the Standard Model with Increased Biological Realism and Reduced Computational Complexity

    Journal of Theoretical Biology 393: 218-28 (2016) with Lei Zhao and Toni Gossmann.

    Exact Simulation of Conditioned Wright-Fisher Models

    Journal of Theoretical Biology 363:419-26 (2016) with Lei Zhao and Martin Lascoux.

    Inferring Host Range Dynamics from Comparative Data:

    The Protozoan Parasites of New World Monkeys

    American Naturalist 184:65-74 (2014) with Lucy Weinert and John Welch.

    Complete Numerical Solution of the Diffusion Equation of Random Genetic Drift

    Genetics 194: 973-985 (2013) with Lei Zhao and Xingye Yue.

    Population Growth Enhances the Mean Fixation Time of Neutral Mutations and the Persistence of Neutral Variation

    Genetics 191: 561-577 (2012)

    A Unified Treatment of the Probability of Fixation When Population Size and the Strength of Selection Change Over Time

    Genetics 188: 907-913 (2011)

    Is Life Impossible?

    Information, Sex and the Origin of Complex Organisms

    Evolution 64: 3300-3309 (2010) with Joel Peck

    Fundamental Insights into the Random Movement of Animals from a Single Distance-Related Statistic

    American Naturalist 174: 506-514 (2009) with Pierre Nouvellet and Jonathan Bacon

    Pleiotropic Scaling of Gene Effects and the 'Cost of Complexity'

    Nature 452: 470-472 (2008) with Günter Wagner, Jane Kenney-Hunt, Mihaela Pavlicev, Joel Peck and James Cheverud

    Fisher's Microscope and Haldane's Ellipse

    American Naturalist 166: 447-457 (2005) with John Welch

    Sympatric Speciation by Sexual Conflict

    PNAS 99, 10533-10538 (2002) with Sergey Gavrilets

    Mutation and Sex in a Competitive World

    Nature 406: 399-403 (2000) with Joel Peck

    Pleiotropy and the Preservation of Perfection

    Science 279: 1210-1213 (1998) with Joel Peck

    Why do Asexual and Self Fertilizing Populations Tend to Occur in Marginal Environments

    Nature 391: 889-892 (1998) with Joel Peck and John Yearsley