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人员

  • 尤佳(青年研究员)
  • 研究方向:机器学习、生物医学大数据挖掘
  • 电子邮箱:jiayou@fudan.edu.cn
  • 个人网站:
  • 简要介绍:尤佳,复旦大学类脑智能科学与技术研究院青年研究员,2020年于香港大学获统计学博士学位。主要从事大数据挖掘方法与生物/临床医学相关的交叉研究,尤其是运用跨模态、多组学数据对脑重大疾病的智能诊断与预测。相关成果以第一作者(含共一) 发表于Nature Human Behaviour(两篇)、Nature Aging、Nature Communications、eClinicalMedicine、Molecular Psychiatry、Neurology等国际综合性期刊和领域内顶刊。成果被Nature主刊撰文报道,被选为Nature Aging研究简报、Nature Review Neurology亮点研究、Nature Aging TOP 1%论文、Neurology编辑评述。入选上海市浦江人才(2023)、中国博士后国(境)外交流“引进项目”(2021),脑科学前沿中心“珠峰青年学者”(2021)。此外,以主要学术骨干参与参与科技创新2030-“脑科学与类脑研究”重大项目、科技部国家重点研发计划-“主动健康和人口老龄化科技应对”等项目。
  • 代表成果:

    1. You J.*, Guo Y.*, Zhang Y., et al., Plasma proteomic profiles predict individual future health risk, Nature Communications, 2023, doi:10.1038/ s41467-023-43575-7.

    2. You J.*, Zhang Y.R.*, Wang H.F., et al., Development of a novel dementia risk prediction model in the general population: A large, longitudinal, population-based machine-learning study, eClinicalMedicine, 2022, doi:10.1016/j.eclinm.2022.101665.

    3. You J.*, Guo Y.*, Wang H.F., et al., Clinical Trajectories Preceding Incident Dementia Up to 15 Years Before Diagnosis: A Large Prospective Cohort Study, Molecular Psychiatry, 2024, doi:10.1038/s41380-024-02570-0.

    4. You J.*, Wang L.B.*, Kang J.J., et al., Prediction of future Parkinson's disease using plasma proteins combined with clinical-demographic measures, Neurology, 2024, doi:10.1212/WNL.0000000000209531

    5. Chen S.D.*, You J.*, Zhang W.*, et al., The genetic architecture of human hypothalamus and its involvement in neuropsychiatric behaviours and disorders, Nature Human Behaviour, 2024, doi:10.1038/s41562-023-01792-6.

    6. Guo Y.*, You J.*, Zhang Y.*, et al., Plasma proteomic profiles predict future dementia in healthy adults, Nature Aging, 2024, doi:10.1038/ s43587-023-00565-0.

    7. Guo Y.*, Chen S.D.*, You J.*, et al., Multiplex cerebrospinal fluid proteomics identifies biomarkers for diagnosis and prediction of Alzheimer's disease, Nature Human Behaviour, 2024, doi:10.1038/s41562-024-01924-6.