Xiao Chang-Institute of Science and Technology for Brain-inspired Intelligence

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Xiao Chang
Research Direction：Clinical Neuroscience; Brain Connectome
Email：xchang@fudan.edu.cn
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Brief Introduction：Dr Xiao Chang is an Associate Researcher at Institute of Science and Technology for Brain-Inspired Intelligence (ISTBI), Fudan University. Dr. Chang’s research focuses on the imaging-genetic mechanisms of common psychiatric disorders such as schizophrenia and depression. By integrating neuroimaging, genetic data, and computational modeling, her work aims to uncover how alterations in brain structure, function, and neurochemistry relate to clinical symptoms, cognitive dysfunction, and underlying pathophysiological processes. Dr. Chang received her bachelor's degree in Materials Physics from Northwestern Polytechnical University in 2011, a master's degree in Psychology from the Fourth Military Medical University in 2014, and a Ph.D. in Clinical and Experimental Neuroscience from Utrecht University in 2019. Afterwards, Dr. Chang joined the Institute of Psychiatry, Psychology and Neuroscience at King’s College London as a postdoctoral researcher from 2019 to 2020. Dr. Chang has received research grants from the National Key R&D Program of China, the National Natural Science Foundation of China, and the Shanghai Science and Technology Commission. She is also a recipient of the "Everest Talent Program" from the Frontier Science Center for Brain Science, Ministry of Education.
Achievement：

1. Runye Shi#, Xiao Chang#, et al, Xiaolei Lin*, Jianfeng Feng*, IMAGEN Consortium. Gene-Environment interactions in the influence of maternal education on adolescent neurodevelopment using ABCD Study. Science Advances, 2024, 10(46):eadp3751.
2. Yuchao Jiang#, Xiao Chang#, Jianfeng Feng*. Towards a unified theory of the aetiology of schizophrenia. British Journal of Psychiatry. 2024, 225(2):299-301. 3.
3. Long-Biao Cui#*, Xian-Yang Wang#, Yu-Fei Fu#, Xiao-Fan Liu#, et al, Fanglin Guan*, Xiao Chang*. Transcriptional level of inflammation markers associates with short-term brain structural changes in first-episode schizophrenia. BMC Medicine, 2023, 21, 250:1-13.
4. Xiao Chang#, Qiyong, Chunbo Li, Weihua Yue, Xin Yu, Shuqiao Yao*, Jianfeng Feng*. Psychiatric disorders in China: strengths and challenges of contemporary research and clinical services. Psychological Medicine, 2021, 51(12):1-14.
5. Xiao Chang#, Wei Zhao, Jujiao Kang, Shitong Xiang, Chao Xie, Hugo Corona-Hernández, Lena Palaniyappan*, Jianfeng Feng*. Language abnormalities in schizophrenia: binding core symptoms through contemporary empirical evidence. Schizophrenia. 2022, 12;8(1):95:1-12.
6. Xiao Chang#*, René C.W. Mandl, Ofer Pasternak, Rachel M. Brouwer, Wiepke Cahn, Guusje Collin. Diffusion MRI derived freewater imaging measures in patients with schizophrenia and their non-psychotic siblings. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2021, 110238, 1-9.