Jingqi Chen-Institute of Science and Technology for Brain-inspired Intelligence

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Jingqi Chen
Research Direction：understanding the roles of noncoding genome in neurological diseases
Email：jingqichen@fudan.edu.cn
Website：https://www.researchgate.net/profile/Jingqi_Chen

Brief Introduction：Dr Chen graduated from Fudan university with a Ph.D. in bioinformatics, and did her postdoctoral research in University of California, Berkeley. Dr Chen joined ISTBI Fudan in Janurary, 2019. Dr Chen mainly studies the roles of the noncoding genome in neurological and psychiatric diseases, through multi-omics data-driven approaches. In particular, current research goals include: (1) understanding the genetic roles and clinical impact of rare SNPs and SVs in Alzheimer's disease and Schizophrenia; (2) identifying and interpreting disease-relevant repeat elements/endogenous retrovirus in the context of brain disorders. Both goals are powered by big and diversed local and public data, and the design of biologically meaningful bioinformatics methods. Welcome to join our research! Please contact Dr Chen at jingqichen @ fudan.edu.cn if interested in PHD/postdoc positions.
Achievement：

1.J Chen*, L Song, A Yang, G Dong, and X-M Zhao*. Disrupted long-range gene regulations elucidate shared tissue-specific mechanisms of neuropsychiatric disorders.Mol Psychiatry. doi: 10.1038/s41380-022-01529-3 (2022)

2.G Dong, J Feng, F Sun,J Chen* and X-M Zhao*. A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank.Genome Med. doi: 10.1186/s13073-021-00927-6 (2021)

3.A Modzelewski#, W Shao#,J Chen, A Lee, X Qi, M Noon, K Tjokro, G Sales, A Biton, A Anand, T Speed, Z Xuan, T Wang*, D Risso*, and L He*. A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development.Cell. doi: 10.1016/j.cell.2021.09.021 (2021)

4.X Zhao#,J Chen#, P Xiao, J Feng, Q Nie, and X-M Zhao. Identifying age-specific gene signatures of the human cerebral cortex with joint analysis of transcriptomes and functional connectomes.Brief Bioinform. doi: 10.1093/bib/bbaa388 (2021)

5.J Chen. A Fully-automated Event-based Variant Prioritizing Solution to the CAGI5 Intellectual Disability Gene Panel Challenge.Hum Mutat. doi:10.1002/humu.23781 (2019)

6.J Chenand W Tian.Explaining the disease phenotype of intergenic SNP through predicted long range regulation.Nucleic Acids Res.doi:10.1093/nar/gkw519 (2016)

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