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  • Linbo Wang
  • Research Direction：computational biology, bioinformatics
  • Email：linbowang@fudan.edu.cn
  • Website：https://faculty.fudan.edu.cn/wanglinbo/zh_CN/index.htm
  • Brief Introduction：He completed his doctoral studies at the School of Life Sciences, Fudan University in 2018. Subsequently, he undertook postdoctoral research at the Institute of Brain and Intelligence Science and Technology, Fudan University, and joined the faculty of Fudan University upon completing the postdoctoral program in 2022. His research focuses on: (1) Multiscale mechanisms of brain disorders; (2) Algorithm development for biomedical big data; (3) Single-cell and spatial multi-omics of human brain evolution. He has served as principal investigator on several projects, including a National Natural Science Foundation of China (NSFC) Young Scientists Fund, a Shanghai Natural Science Foundation General Program, and a sub-project of the Shanghai Municipal Major S&T Program on “Brain and Brain-Inspired Intelligence: Basic Research and Translational Applications.”To date, he has published over ten SCI papers as first or corresponding author in journals such as Neurology, Translational Psychiatry, npj Aging, and Communications Biology.
  • Achievement：

    1.Pan, Guoqing*; Zhang, Yi; Kang, Ju-Jiao; jiang, Yuchao; zhang, Wei; Ren, Peng; You, Jia; Gong, Weikang; Yu, Jin-Tai; Feng, Jian-Feng; Zhang, Xuejuan; Cheng, Wei#; Wang, Linbo#, Modifiable traits and genetic associations with grey matter volume in mid-to-late adulthood: a population-based study in the UK biobank. npj Aging, 2025, 11(1): 67.

    2.He Siyu*, Li Zeyu*, Zeng Feng*, Jin Yifei*, Zhang Wei, Chen Xinyi, Zhang Zequn, Cheng, Wei, Wang, Linbo#, Wenze Xiao#, and Mei Qiyong#, Immunometabolic and Brain Structural Alterations Mediate Increased Risk of Brain Diseases in Rheumatoid Arthritis Patients. Translational Psychiatry, 2025, 15(1):443.

    3.Wang, Yu-Jia*; Zhou, Zairen*; Li, Yu-Zhu; Kang, Ju-Jiao; Yu, Jin-Tai; Feng, Jian-Feng; Cheng, Wei; Pan, Guoqing#; You, Jia#; Wang, Linbo#, Temporal trends of blood-based markers in various psychiatric disorders and their cross-sectional brain structure associations. Communications Medicine, 2025, 5(1): 239.

    4.You, Jia*; Wang, Linbo*,#; Wang, Yujia; Kang, Jujiao; Yu, Jintai; Cheng, Wei#; Feng, Jianfeng#; Prediction of Future Parkinson Disease Using Plasma Proteins Combined With Clinical-Demographic Measures, Neurology, 2024, 103(3): e209531(1)-e209531(13).

    5.Zheng, Liping*; Zhou, Cheng*; Mao, Chengjie*; Xie, Chao; You, Jia; Cheng, Wei; Liu,Chunfeng; Huang, Peiyu; Guan, Xiaoujun; Guo, Tao; Wu, Jingjing; Luo, Yajun; Xu, Xiaojun; Zhang,Baorong; Zhang, Minming#; Wang, Linbo#; Feng, Jianfeng#; Contrastive machine learning reveals Parkinson's disease specific features associated with disease severity and progression, Communications Biology, 2024, 7(1): 1-11.

    6.Zhou, Cheng*; You, Jia*; Guan, Xiaojun; Guo, Tao; Wu, Jingjing; Wu, Haoting; Wu, Chenqing; Chen, Jingwen; Wen, Jiaqi; Tan, Sijia; Duanmu, Xiaojie; Qin, Jianmei; Huang, Peiyu; Zhang, Baorong; Cheng, Wei; Feng, Jianfeng; Xu, Xiaojun#; Wang, Linbo#; Zhang, Minming#, Microstructural alterations of the hypothalamus in Parkinson's disease and probable REM sleep behavior disorder, Neurobiology of Disease, 2024, 194: 106472.

    7.Guoqing, Pan*; Yuchao, Jiang; Wei, Zhang; Xuejuan, Zhang; Linbo, Wang#; Wei, Cheng#, Identification of Parkinson's disease subtypes with distinct brain atrophy progression and its association with clinical progression, Psychoradiology, 2024, 4.

    8.Wang, Linbo*; Zhou, Cheng*; Zhang, Wei; Zhang, Minming#; Cheng, Wei#; Feng, Jianfeng#; Association of Cortical and Subcortical Microstructure With Clinical Progression and Fluid Biomarkers in Patients With Parkinson Disease, Neurology, 2023, 101(3): e209531(1)- e209531(11).

    9.Zhou Cheng*; Wang Linbo*; Cheng Wei#; Lv JinChao; Guan Xiaoujun; Guo Tao; Wu Jingjing; Zhang Wei; Gao Ting; Liu Xiaocao; Bai Xueqin; Wu Haoting; Cao Zhengye; Gu Luyan; Chen Jingwen; Wen Jiaqi; Huang Peiyu; Xu Xiaojun; Zhang Baorong; Feng Jianfeng#; Zhang Minming#, Two distinct trajectories of clinical and neurodegeneration events in Parkinson’s disease, npj Parkinson's Disease, 2023, 9(1): 111.

    10.Wang Linbo*; Wu Ping*; Brown Peter; Zhang Wei; Liu Feng-Tao; Han Yan; Zuo Chuan-Tao#; Chen Wei#; Feng Jian-Feng#; Association of Structural Measurements of Brain Reserve With Motor Progression in Patients With Parkinson Disease, Neurology, 2022, 99(10): e977-e988.

    11.Wang, Linbo*; Zhou, Cheng*; Cheng, Wei#; Rolls, Edmund T.; Huang, Peiyu; Ma, Ningning; Liu, Yuchen; Zhang, Yajuan; Guan, Xiaojun; Guo, Tao; Wu, Jingjing; Gao, Ting; Xuan, Min; Gu, Quanquan; Xu, Xiaojun; Zhang, Baorong; Gong, Weikang; Du, Jingnan; Zhang, Wei; Feng, Jianfeng#; Zhang, Minming#, Dopamine depletion and subcortical dysfunction disrupt cortical synchronization and metastability affecting cognitive function in Parkinson's disease, Human Brain Mapping, 2021, June: 1--13.

    12.Wang Linbo*; Cheng Wei*,#; Rolls Edmund; Dai Fu-Li; Gong Wei-Kang; Du Jing-Nan; Zhang Wei; Wang Shou-Yan; Liu Feng-Tao; Wang Jian; Brown Peter#; Feng Jian-Feng#; Association of specific biotypes in patients with Parkinson disease and disease progression, Neurology, 2020, 95(11): e1445-e1460.

    *Equally contributed first author; #Corresponding author.


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