简介：膜片钳电生理记录系统常用于组织切片、单个分离细胞或一小块细胞膜的离子电流记录。该技术常应用于突触可塑性、神经元突触传递、细胞膜离子通道的性质鉴定及其动力学、细胞分泌、细胞信号转导等研究，记录神经元、心肌细胞、肌细胞和胰岛β细胞等可兴奋性细胞。

The patch-clamp is a versatile electrophysiological tool to record ion currents through whole-cell or patch and study ion channels from cultured single-cell or tissue section. The technique is widely used to study excitable cells, including neurons, cardiomyocytes and muscle fibers, in physiological and pharmacological research. It is used for the study of synaptic plasticity, neuronal synaptic transmission, characterization and dynamics of ion channels on cell membrane, cell secretion, and cell signal transduction.

Position：张江校区行政楼202

Person in charge：Yiling NI

Contact information：cnc_istbi@fudan.edu.cn

规格配置：

1、MultiClamp 700B 双通道放大器

2、Digidata 1550B 模数转换器

3、pCLAMP 11 采集分析软件

4、FN1 Nikon显微镜系统

5、Master-8程序刺激器

6、Sutter微操精度40nm